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Tadalafil, a phosphodiesterase type 5 inhibitor, improves bladder blood supply and restores the initial phase of lower urinary tract dysfunction in diabetic rats.

Daisuke GotohKazumasa TorimotoYoshihiro TatsumiShunta HoriAtsushi YamadaMakito MiyakeYosuke MorizawaKatsuya AokiNobumichi TanakaAkihide HirayamaKiyohide Fujimoto
Published in: Neurourology and urodynamics (2017)
Tadalafil improves bladder blood supply and lower urinary tract function in diabetic rats. Tadalafil may be a promising drug that restores lower urinary tract dysfunction in the early phase of diabetes.
Keyphrases
  • urinary tract
  • diabetic rats
  • oxidative stress
  • lower urinary tract symptoms
  • benign prostatic hyperplasia
  • type diabetes
  • cardiovascular disease
  • emergency department
  • glycemic control
  • insulin resistance