Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population.
Bo SongYamei WangXiuzhi ZhuLi ZhangHui ZhouHongmei ZhangTian-Liang ZhangWansheng JiPublished in: BioMed research international (2021)
The aim of the present work was to investigate the risk factors for gastric cancer- (GC-) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic diseases included in the case group and the remaining 265 in the control group, were enrolled. The relevant data for the participants, including general information (gender, age, smoking, and drinking), comorbidities (diabetes, hypertension, and anemia), tumor-related data (tumor site, histology, degree of differentiation, and clinical stage), and treatment-related data (surgery, chemotherapy, hormones, transfusion, and peripherally inserted central venous catheter (PICC)), were collected. Statistically significant factors derived from univariate analyses were then subjected to multivariate logistic regression analyses. The results demonstrate a statistically significant difference in age, diabetes, hypertension, histology, surgery, chemotherapy, and PICC (P < 0.05), compared with control. Age, diabetes, surgery, and PICC serve as independent risk factors for GC-associated thrombotic diseases (P < 0.05). The present work demonstrates that GC-associated thrombotic diseases are significantly associated with age, diabetes, surgery, and PICC, suggesting a potential target for early detection and preventive strategy for GC patients with thrombophilia.
Keyphrases
- minimally invasive
- coronary artery bypass
- type diabetes
- cardiovascular disease
- glycemic control
- blood pressure
- electronic health record
- gas chromatography
- surgical site infection
- end stage renal disease
- chronic kidney disease
- big data
- ejection fraction
- mental health
- squamous cell carcinoma
- healthcare
- prognostic factors
- data analysis
- acute kidney injury
- metabolic syndrome
- adipose tissue
- health information
- peritoneal dialysis
- social media
- smoking cessation
- climate change
- combination therapy
- human health
- weight loss