A better scoring model for de novo peptide sequencing: the symmetric difference between explained and measured masses.
Thomas TschagerSimon RöschLudovic GilletPeter WidmayerPublished in: Algorithms for molecular biology : AMB (2017)
We conclude that considering the symmetric difference as optimization goal can improve the identification rates for de novo peptide sequencing. A preliminary version of this work has been presented at WABI 2016.