Lighter serum copper isotopic composition in patients with early non-alcoholic fatty liver disease.
Sanne Van CampenhoutAgustina A M B HastutiSander LefereHans Van VlierbergheFrank VanhaeckeMarta Costas-RodríguezLindsey DevisscherPublished in: BMC research notes (2020)
Our results showed that serum δ65Cu values were lower in NAFLD patients, already at the level of simple steatosis, and remained stable during further disease progression. ROC analysis shows an almost perfect diagnostic ability of serum δ65Cu values for NAFLD, but no discrimination between different severity degrees could be made. Therefore, the serum Cu isotopic composition might show potential for early diagnosis of NAFLD patients.