Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging.
Gregory W AlbersMichael P MarksStephanie KempSoren ChristensenJenny P TsaiSantiago Ortega-GutierrezRyan A McTaggartMichel T TorbeyMay Kim-TenserThabele Leslie-MazwiAmrou SarrajScott E KasnerSameer A AnsariSharon D YeattsScott HamiltonMichael MlynashJeremy J HeitGreg ZaharchukSun KimJanice CarrozzellaYuko Y PaleschAndrew M DemchukRoland BammerPhilip W LavoriJoseph P BroderickMaarten G Lansbergnull nullPublished in: The New England journal of medicine (2018)
Endovascular thrombectomy for ischemic stroke 6 to 16 hours after a patient was last known to be well plus standard medical therapy resulted in better functional outcomes than standard medical therapy alone among patients with proximal middle-cerebral-artery or internal-carotid-artery occlusion and a region of tissue that was ischemic but not yet infarcted. (Funded by the National Institute of Neurological Disorders and Stroke; DEFUSE 3 ClinicalTrials.gov number, NCT02586415 .).
Keyphrases
- middle cerebral artery
- internal carotid artery
- atrial fibrillation
- healthcare
- acute ischemic stroke
- cerebral ischemia
- high resolution
- case report
- magnetic resonance imaging
- ischemia reperfusion injury
- mass spectrometry
- computed tomography
- subarachnoid hemorrhage
- mesenchymal stem cells
- bone marrow
- replacement therapy