Login / Signup

Hibiscus flower extract selectively induces apoptosis in breast cancer cells and positively interacts with common chemotherapeutics.

Christopher NguyenKiruthika BaskaranAlaina PupulinIvan RuvinovOla ZaitoonSahibjot GrewalBenjamin ScariaAli MehaidliCaleb VeghSiyaram Pandey
Published in: BMC complementary and alternative medicine (2019)
Hibiscus extract is effective on breast cancer, most notably on generally resistant triple-negative breast cancer, while being selective for normal healthy cells. Hibiscus extract could supplement chemotherapeutic regimens as an adjuvant and lead to a more efficacious treatment approach to reduce chemotherapy dosages and related toxicity.
Keyphrases
  • oxidative stress
  • induced apoptosis
  • breast cancer cells
  • anti inflammatory
  • cell cycle arrest
  • squamous cell carcinoma
  • cell death
  • locally advanced
  • endoplasmic reticulum stress
  • drug induced