A pilot study of essential tremor: cerebellar GABA+/Glx ratio is correlated with tremor severity.

Sofie TapperNathanael GöranssonPeter LundbergAnders TisellPeter Zsigmond

Published in: Cerebellum & ataxias (2020)

We demonstrated a positive correlation between increasing tremor disability and the ratio of GABA+/ Glx in the cerebellum of essential tremor patients. This highlights the impact of an altered balance of the excitatory and inhibitory neurotransmitters in tremor severity. Rather than a change in GABA+, which was constant, we attribute this finding to an overall decrease of Glx.

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