Clinical risk associated with COVID-19 among 86000 patients with congenital heart disease.
Simon G WilliamsSimon FrainHui GuoMatthew J CarrDarren M AshcroftBernard D KeavneyPublished in: Open heart (2023)
In this study of the COVID-19 pandemic experience, using population health records in over 86000 patients with CHD in England, patients with CHD with COVID-19 were at around 50-75% higher risk of hospitalisation and mortality compared with matched controls with COVID-19. We provide the first primary care-derived estimates for COVID-19 hospitalisation and case-fatality rates in patients with CHD. Some factors predictive of worse COVID-19 outcome in general populations (such as non-white ethnic group), and other CHD-specific comorbidities (such as pulmonary hypertension), influenced outcomes among patients with CHD.
Keyphrases
- coronavirus disease
- sars cov
- primary care
- congenital heart disease
- pulmonary hypertension
- respiratory syndrome coronavirus
- cardiovascular disease
- type diabetes
- insulin resistance
- cardiovascular events
- pulmonary artery
- skeletal muscle
- adipose tissue
- coronary artery disease
- pulmonary arterial hypertension
- glycemic control