Effect of enamel matrix derivative liquid in combination with a natural bone mineral on new bone formation in a rabbit GBR model.

Eizaburo KobayashiMasako Fujioka-KobayashiNikola SaulacicBenoit SchallerAnton SculeanRichard J Miron

Published in: Clinical oral implants research (2019)

The addition of EMD-liquid did not lead to statistically significant bone formation when compared to NBM alone. The combination of NBM + EMD-liquid but not NBM alone did however induce superior mineralized tissues when compared to control (empty). Further research investigating the adsorption potential of EMD-liquid to bone-grafting particles with/without collagen may provide valuable insights into future regenerative strategies with enamel matrix proteins.

Keyphrases

ionic liquid
stem cells
bone mineral density
bone regeneration
gene expression
mesenchymal stem cells
soft tissue
cell therapy
current status
tissue engineering
bone loss
bone marrow
risk assessment
wound healing
aqueous solution