Photophysics-informed two-photon voltage imaging using FRET-opsin voltage indicators.
F Phil BrooksHunter C DavisPojeong ParkYitong QiAdam E CohenPublished in: bioRxiv : the preprint server for biology (2024)
Voltage sensitivity in FRET-opsin indicators comes from a photocycle intermediate, reachable via optimized 2P excitation.