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Decellularized Descemet Membrane Anterior Keratoplasty With Allogeneic Simple Limbal Epithelial Transplantation for Partial Limbal Stem Cell Deficiency Following Partial Keratolimbal Allograft Failure.

Albert Y CheungCameron B ReinischJoshua H Hou
Published in: Cornea (2024)
DMAK may be a long-term substrate to help improve and maintain epithelization of the cornea up to 1.5 years. DMAK may be a viable alternative to using amniotic membrane as a scaffold in allogeneic simple limbal epithelial transplantation for treatment of partial LSCD. While late epithelial staining recurred in our patient, DMAK appears to prevent recurrent epithelial defects and reduce ocular surface pain, conveying an improvement in quality of life in patients at high risk of rejection/failure.
Keyphrases
  • stem cells
  • stem cell transplantation
  • bone marrow
  • chronic pain
  • cell therapy
  • case report
  • mesenchymal stem cells
  • hematopoietic stem cell
  • extracellular matrix
  • tissue engineering
  • spinal cord injury
  • umbilical cord