Radiotherapy Enhances Metastasis Through Immune Suppression by inducing PD-L1 and MDSC in distal sites.
Yuzhu HouKaiting YangLiangliang WangJiaai WangXiaona HuangAndras PiffkoSean Z LuoXinshuang YuEnyu RaoCarlos MartinezJason BugnoMatthias MackEverett E VokesSean P PitrodaSteven J ChmuraRalph R WeichselbaumHua Laura LiangPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Blockade of PD-L1/CXCL10 axis or MDSC infiltration during radiation can enhance abscopal tumor control and reduce metastasis.