A Stereological Study of the Toxic Effects of Cerium Oxide during Pregnancy on Kidney Tissues in Neonatal NMRI Mice.

Afsaneh NematiVahideh AssadollahiIlaria PelusoAbolfazl AbbaszadehMandana Beigi-BoroujeniZahra KhanipurMohammad Reza Gholami

Published in: Oxidative medicine and cellular longevity (2020)

Our results suggest that high doses of CeO2 impair fetal renal development in pregnant mice, which results in kidney damage. Therefore, CeO2 administration during pregnancy could have dose-dependent adverse effects on the developing kidneys in neonates.

Keyphrases

high fat diet induced
gene expression
oxidative stress
type diabetes
wild type
adipose tissue