A west African ancestry-associated SNP on 8q24 predicts a positive biopsy in African American men with suspected prostate cancer following PSA screening.
Jian GuLisly CheryGraciela M Nogueras GonzálezChad HuffSara StromJeffrey A JonesDonald P GriffithSteven E CanfieldXuemei WangXuelin HuangPamela RobersonQing H MengPatricia TroncosoMichael M IttmannMichael CovinskyMichael ScheurerMargarita Irizarry RamirezCurtis A PettawayPublished in: The Prostate (2024)
This study demonstrated that the west African ancestry-specific SNP rs7824364 on 8q24 independently predicted a positive prostate biopsy in AA men who were candidates for prostate biopsy subsequent to PCa screening.