Sex-Specific Plaque Signature: Uniqueness of Atherosclerosis in Women.
Anum MinhasIlton Cubero SalazarBrigitte KazziAllison G HaysAndrew D ChoiArmin Arbab-ZadehErin Donelly MichosPublished in: Current cardiology reports (2021)
There are sex differences in the prevalence, progression, and prognostic impact of atherosclerosis. Furthermore, developing evidence demonstrates unique differences in atherosclerotic plaque characteristics between men and women on both noninvasive and invasive imaging modalities. Coronary microvascular dysfunction may be present even if no obstructive lesions are found. Most importantly, non-obstructive coronary artery disease is associated with a heightened risk of future adverse cardiovascular events and should not be ignored. The distinct plaque signature in women should be recognized, and optimal preventive strategies should be performed for both sexes.
Keyphrases
- coronary artery disease
- cardiovascular events
- polycystic ovary syndrome
- percutaneous coronary intervention
- coronary artery bypass grafting
- cardiovascular disease
- pregnancy outcomes
- high resolution
- risk factors
- cervical cancer screening
- oxidative stress
- aortic stenosis
- emergency department
- current status
- heart failure
- insulin resistance
- type diabetes
- skeletal muscle
- metabolic syndrome
- atrial fibrillation
- acute coronary syndrome
- left ventricular
- mass spectrometry
- fluorescence imaging