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The prevalence and real-world therapeutic analysis of Chinese patients with KRAS-Mutant Non-Small Cell lung cancer.

Hanxiao ChenDingzhi HuangGen LinXue YangMinglei ZhuoYujia ChiXiaoyu ZhaiBo JiaJingjing WangYuyan WangJianjie LiTongtong AnMeina WuZiping WangJun Zhao
Published in: Cancer medicine (2022)
KRAS is an important driver gene in NSCLC, compromising 12.1% in this study, and G12C was noted as the most common subtype. Patients with KRAS-mutant NSCLC could benefit from pemetrexed-based chemotherapy and ICIs.
Keyphrases
  • wild type
  • small cell lung cancer
  • advanced non small cell lung cancer
  • risk factors
  • brain metastases
  • locally advanced
  • epidermal growth factor receptor
  • squamous cell carcinoma
  • chemotherapy induced