Differential processing of high-molecular-weight kininogen during normal pregnancy.
Stephenie H DrollYen-Michael Sheng HsuSteven K DrakeAshley KimWeixin WangKatherine R CalvoZheng CaoTony Y HuZhen ZhaoPublished in: Rapid communications in mass spectrometry : RCM (2020)
This study demonstrates dynamic changes in HK and naturally occurring HK-derived peptides during pregnancy. Our study sheds light on the gestational changes of HK and its peptides for further validation of them as potential biomarkers for pregnancy-related complications.