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Are statins onco- suppressive agents for every type of tumor? A systematic review of literature.

Luca FilaferroFabiana ZaccarelliGiovanni Francesco NiccoliniAndrea ColizzaFederica ZoccaliMichele GrassoMassimo Fusconi
Published in: Expert review of anticancer therapy (2024)
There are data which correlate statins with a possible tumor suppressive action among the following cancers: breast, lung, prostate and head and neck. Lastly, for gastric cancer and colorectal there is no evidence of a correlation. The onco-suppressive efficacy of statins is mainly related to the histopathological and/or molecular characteristics of the tumor cells, which have different characteristics.
Keyphrases
  • cardiovascular disease
  • prostate cancer
  • electronic health record
  • big data
  • machine learning
  • benign prostatic hyperplasia
  • young adults
  • artificial intelligence
  • drug induced
  • childhood cancer