ATF2/BAP1 Axis Mediates Neuronal Apoptosis After Subarachnoid Hemorrhage via P53 Pathway.

Qi Tian Chengli Liu Jianming Liao Guijun Wang Wenrui Han Xiao-Xing Xiong Zhibiao Chen Lijuan Gu Mingchang Li

Published in: Stroke (2024)

Our results suggest that the neuronal ATF2/BAP1 axis exerts a brain-damaging effect by modulating P53 activity and stability and may be a novel therapeutic target for SAH.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
endoplasmic reticulum stress
brain injury
transcription factor
blood brain barrier
oxidative stress
cell death
signaling pathway
cell cycle arrest
resting state
multiple sclerosis
cell proliferation
white matter