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Influence of gene modification in biological behaviors and responses of mouse lung telocytes to inflammation.

Dongli SongMenglin XuRuixue QiRuihua MaYile ZhouDuojiao WuHao FangXiangdong Wang
Published in: Journal of translational medicine (2019)
We successfully constructed mouse lung telocyte cell-line which maintained the biological properties and behaviors as primary telocytes and could responses to inflammation induced by LPS. Thus, gene-modified lung telocytes, Telocyte Line, would provide a cell tool for researchers exploring the roles and applications of telocytes involved in physiological and pathological states in future.
Keyphrases
  • oxidative stress
  • copy number
  • genome wide
  • single cell
  • wastewater treatment
  • cell therapy
  • gene expression
  • stem cells
  • dna methylation
  • transcription factor