Dickkopf-4 gene expression is associated with differentiation and lymph node metastasis in colorectal cancer.

Yuya TsukuiTatsuya YamaguchiShinya MaekawaShinichi TakanoTadashi SatoNobuyuki Enomoto

Published in: JGH open : an open access journal of gastroenterology and hepatology (2019)

Intratumoral DKK-4 expression, by partly reflecting the Wnt/β catenin pathway, is strongly associated with the advancement of colorectal cancer and OS in colorectal cancer patients with metastasis, although further studies are needed.

Keyphrases

lymph node metastasis
gene expression
squamous cell carcinoma
stem cells
cell proliferation
papillary thyroid