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Combined immunotherapy with nivolumab and ipilimumab with and without local therapy in patients with melanoma brain metastasis: a DeCOG* study in 380 patients.

Teresa AmaralFelix KieckerSarah SchaeferHenner StegeKatharina KaehlerPatrick TerheydenAnja GesierichRalf GutzmerSebastian HaferkampJochen UttikalCarola BerkingDavid Rafei-ShamsabadiLydia ReinhardtFriedegund MeierAnte KaroglanChristian PoschThilo GambichlerClaudia PfoehlerKai ThomsJulia TietzeDirk DebusRudolf HerbstSteffen EmmertCarmen LoquaiJessica C HasselFrank MeissThomas TuetingVanessa HeinrichThomas EigentlerClaus GarbeLisa Zimmernull null
Published in: Journal for immunotherapy of cancer (2021)
Immunotherapy with nivolumab plus ipilimumab, particularly in combination with stereotactic radiosurgery or surgery improves OS in asymptomatic and symptomatic MBM.
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