The Cross-talk Between Intestinal Microbiota and MDSCs Fuels Colitis-associated Cancer Development.
Hadas Ashkenazi-PreiserOr ReuvenAtara Uzan-YulzariSharon KomisarovRoy CirkinSondra C TurjemanCarmel EvenNira TwaikKerem Ben-MeirIvan MikulaLeonor Cohen-DanielYaron MeirowEli PikarskyYoram LouzounOmry KorenMichal BaniyashPublished in: Cancer research communications (2024)
MDSCs-dysbiotic bacteria interactions in the intestine play a crucial role in intensifying immunosuppression within the CAC microenvironment, ultimately facilitating tumor growth, highlighting potential therapeutic targets for improving the treatment outcomes of CAC.