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Myocardial Function in Premenopausal Women Treated With Ovarian Function Suppression and an Aromatase Inhibitor.

Jennifer H JordanRalph B D'AgostinoKatherine AnsleyEmily DouglasSusan MelinSteven SorscherSujethra VasuSung ParkAnuj KotakPaul A RomittiNathanial S O'ConnellWilliam G HundleyAlexandra Thomas
Published in: JNCI cancer spectrum (2021)
Over the brief interval examined, women with HR-positive breast cancer receiving OFS with an aromatase inhibitor experienced reductions in adenosine-associated changes in LV myocardial T1 relative to women who received nonhormonal therapy for TNBC. These findings suggest a possible adverse impact on LV myocardial microcirculatory function in premenopausal women with breast cancer receiving hormone deprivation therapy.
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