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CT radiomics associations with genotype and stromal content in pancreatic ductal adenocarcinoma.

Marc A AttiyehJayasree ChakrabortyCaitlin A McIntyreRajya KappagantulaYuting ChouGokce AskanKenneth SeierMithat GonenOlca BasturkVinod P BalachandranT Peter KinghamMichael I D'AngelicaJeffrey A DrebinWilliam R JarnaginPeter J AllenChristine A Iacobuzio-DonahueAmber L SimpsonRichard Kinh Gian Do
Published in: Abdominal radiology (New York) (2020)
In this study, we demonstrate that in PDAC SMAD4 status and tumor stromal content can be predicted using radiomic analysis of preoperative CT imaging. These data show an association between resectable PDAC imaging features and underlying tumor biology and their potential for future precision medicine.
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