Dopamine transporter binding in the brain is linked to irritable bowel syndrome in Parkinson's disease.

Kirsi MurtomäkiJuho JoutsaTuomas MertsalmiElina JaakkolaElina MäkinenReeta LevoMikael EklundSimo NuuttilaEero PekkonenTommi NoponenToni IhalainenValtteri KaasinenFilip Scheperjans

Published in: Brain and behavior (2023)

These findings suggest that PD patients with IBS may have higher DAT binding in the right hemisphere. This finding implicates alterations of brain neurotransmitter physiology in the gastrointestinal symptoms of PD patients.

Keyphrases

irritable bowel syndrome
end stage renal disease
resting state
newly diagnosed
white matter
ejection fraction
chronic kidney disease
prognostic factors
binding protein
functional connectivity
cerebral ischemia
metabolic syndrome
dna binding
transcription factor
uric acid