Cohorting KPC+ Klebsiella pneumoniae (KPC-Kp)-positive patients: A genomic exposé of cross-colonization hazards in a long-term acute-care hospital (LTACH).
Shawn E WhitefieldMary K HaydenKaren LolansRachel D YelinRobert A WeinsteinMichael Y LinEvan S SnitkinPublished in: Infection control and hospital epidemiology (2020)
Acquisition of secondary KPC-Kp isolates carrying distinct antibiotic resistance genes was detected in nearly half of cohorted patients. These results highlight the importance of healthcare provider adherence to infection prevention protocols within cohort locations, and they indicate the need for future studies to assess whether multiple-strain acquisition increases risk of adverse patient outcomes.
Keyphrases
- klebsiella pneumoniae
- healthcare
- end stage renal disease
- acute care
- ejection fraction
- newly diagnosed
- antibiotic resistance genes
- escherichia coli
- multidrug resistant
- chronic kidney disease
- primary care
- peritoneal dialysis
- wastewater treatment
- type diabetes
- patient reported outcomes
- skeletal muscle
- gene expression
- social media
- patient reported
- anaerobic digestion
- genome wide