Placental pathology in sudden intrauterine death (SIUD) in SARS-CoV-2-positive oligosymptomatic women.

Lars-Christian HornIrene KrückenGrit Gesine Ruth HillerMaria NiedermairKristina PeracCorinna PietschAnne Kathrin Höhn

Published in: Archives of gynecology and obstetrics (2022)

Sudden intrauterine death may occur in mothers who are oligosymptomatic for COVID-19. Acute placental failure is responsible for SIUD, demonstrated by massive perivillous fibrin deposits and extensive necroses of the villous trophoblast with SARS-CoV-2-positivity based on immunohistochemical staining and RT-PCR. Detailed histopathological examination of placental and fetal tissue is mandatory to verify SARS-CoV-2 and to evaluate the pathogenesis and functionality of this disease.

Keyphrases

sars cov
respiratory syndrome coronavirus
liver failure
polycystic ovary syndrome
respiratory failure
pregnant women
skeletal muscle
pregnancy outcomes
aortic dissection
drug induced
acute respiratory distress syndrome
insulin resistance
breast cancer risk
platelet rich plasma