Effects of chronic mild hyperoxia on retinal and choroidal blood flow and retinal function in the DBA/2J mouse model of glaucoma.

Eric R MuirSaurav B ChandraDivya NarayananVincent ZhangIke ZhangZhao JiangJeffrey W KielTimothy Q Duong

Published in: PloS one (2022)

This study investigated the effects of chronic mild hyperoxia on retinal function and on retinal and choroidal blood flow in a mouse model of glaucoma. Retinal function was improved in the O2-treated mice at late stage, despite a progressive decline of RBF and ChBF with age that was comparable to untreated mice.

Keyphrases

optical coherence tomography
blood flow
optic nerve
diabetic retinopathy
mouse model
multiple sclerosis
high fat diet induced
metabolic syndrome
skeletal muscle
newly diagnosed
atomic force microscopy
wild type
insulin resistance