Survival benefit of nephroureterectomy in systemic therapy exposed metastatic upper tract urinary urothelial carcinoma patients.

Simone MorraReha-Baris IncesuLukas ScheipnerAndrea BaudoLetizia Maria Ippolita JannelloCarolin SiechMario de AngelisZhe TianMassimiliano CretaGianluigi CalifanoClaudia Collà RuvoloFred SaadShahrokh F ShariatFelix K H ChunOttavio de CobelliGennaro MusiAlberto BrigantiDerya TilkiSascha AhyaiLuca CarmignaniNicola LongoPierre I Karakiewicz

Published in: World journal of urology (2024)

In mUTUC patients, treated with ST, NU drastically improved survival in T1-T2 patients, even after strict methodological adjustments (multivariable and landmark analyses). However, this survival benefit did not apply to patients with locally more advanced disease (T3-T4).

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
small cell lung cancer
squamous cell carcinoma
prognostic factors
stem cells
patient reported
replacement therapy