Water intake, thirst, and copeptin responses to two dehydrating stimuli in lean men and men with obesity.
Douglas C ChangAdela PenesovaJoy C BuntEmma J StinsonStavros A KavourasMarci E GluckEthan PaddockMary WalterPaolo PiaggiJonathan KrakoffPublished in: Obesity (Silver Spring, Md.) (2022)
Diminished thirst and copeptin responses are part of the obesity phenotype and may be influenced by leptin. Adiposity may impact pathways regulating thirst and vasopressin release, warranting further investigation.