Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis.
Dan ShaoWenxiang ShenYuyang MiaoZhen GaoMenghao PanQiang WeiZuoting YanXiaoe ZhaoBaohua MaPublished in: Journal of animal science and biotechnology (2023)
These results indicate that the natural compound SFN has a preventive effect on LPS-induced inflammation through by regulating the Nrf2-mediated autophagy pathway in primary goat mammary epithelial cells and a mouse model of mastitis, which may improve prevention strategies for mastitis in dairy goats.