Classification of the acute emetogenicity of chemotherapy in pediatric patients: A clinical practice guideline.
Edric Paw Cho SingPaula D RobinsonJacqueline FlankMark HoldsworthJennifer ThackrayJason Lawrence FreedmanPaul GibsonAndrea D OrseyPriya PatelRobert PhillipsCarol PortwineJennifer L RaybinSandra CabralLillian SungL Lee DupuisPublished in: Pediatric blood & cancer (2019)
This clinical practice guideline (CPG) provides clinicians with recommendations regarding chemotherapy emetogenicity classification in pediatric oncology patients. This information is critically important for the appropriate selection of antiemetic prophylaxis. Recommendations are based on a systematic review limited to pediatric patients and a framework for classification when antiemetic prophylaxis is provided. Findings of 87 publications informed the emetogenicity classification of 49 single-agent and 13 combination-agent regimens. Information required for the classification of many chemotherapies commonly administered to pediatric patients is lacking. In the absence of pediatric data, consultation of methodologically sound CPGs aimed at adult oncology patients may be appropriate.
Keyphrases
- deep learning
- machine learning
- end stage renal disease
- palliative care
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- healthcare
- patient reported outcomes
- dna methylation
- big data
- artificial intelligence
- gene expression
- electronic health record
- radiation therapy
- chemotherapy induced
- patient reported
- young adults
- acute respiratory distress syndrome
- data analysis