Dexmedetomidine reduces cranial temperature in hypothermic neonatal rats.
Ryan M McAdamsRonald J McPhersonRaj KapurBrian PhillipsDanny D ShenChristopher M TraudtPublished in: Pediatric research (2015)
Prolonged DEX treatment in neonatal rats was not associated with abnormal brain histology. These data provide reassuring preliminary results for using DEX with therapeutic hypothermia to treat near-term brain injury.