SCN1A Variants in vaccine-related febrile seizures: A prospective study.

John A Damiano Lucy DengWenhui LiRosemary BurgessAmy L SchneiderNigel W CrawfordJim ButteryMichael GoldPeter RichmondKristine K MacartneyMichael S HildebrandIngrid Eileen SchefferNicholas WoodSamuel Frank Berkovic

Published in: Annals of neurology (2019)

Pathogenic SCN1A variants may be identified in infants with vaccine-proximate febrile seizures. As early diagnosis of Dravet syndrome is essential for optimal management and outcome, SCN1A sequencing in infants with prolonged febrile seizures, proximate to vaccination, should become routine. ANN NEUROL 2020;87:281-288.

Keyphrases

urinary tract infection
copy number
chemotherapy induced
temporal lobe epilepsy
single cell
clinical practice
case report
genome wide