Extracellular vesicles from young women's breast cancer patients drive increased invasion of non-malignant cells via the Focal Adhesion Kinase pathway: a proteomic approach.

Kimberly R JordanJessica K HallTroy SchedinMichelle BorakoveJenny J XianMonika DzieciatkowskaTraci R LyonsPepper SchedinKirk C HansenVirginia F Borges

Published in: Breast cancer research : BCR (2020)

Our results suggest that the proteome of EVs from breast cancer patients reflects their functionality in tumor motility assays and may help elucidate the role of EVs in breast cancer progression.

Keyphrases

induced apoptosis
biofilm formation
cell migration
high throughput
endoplasmic reticulum stress
signaling pathway
staphylococcus aureus
oxidative stress
young adults
cystic fibrosis
candida albicans
single cell