Comparison of dronedarone vs. flecainide in the maintenance of sinus rhythm, following electrocardioversion in adults with persistent atrial fibrillation: a systematic review and meta-analysis.
Hannah WilsonDeclan PattonZena E H MooreTom O'ConnorLinda Elizabeth NugentPublished in: European heart journal. Cardiovascular pharmacotherapy (2022)
Dronedarone and flecainide displayed similar efficacy in maintaining SR in patients following electrocardioversion for persistent AF. The SR maintenance was numerically but not statistically significant in the flecainide group. Side effects uncovered similar pro-arrhythmic activity. However, in light of the deficiency of volume and quality of available evidence, the writer acknowledges the requirement for future research.
Keyphrases
- atrial fibrillation
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- left atrial
- peritoneal dialysis
- left atrial appendage
- catheter ablation
- percutaneous coronary intervention
- direct oral anticoagulants
- blood pressure
- left ventricular
- heart rate
- patient reported outcomes
- venous thromboembolism
- acute coronary syndrome
- smoking cessation
- patient reported