Direct identification of neoantigen-specific TCRs from tumor specimens by high-throughput single-cell sequencing.
Yong-Chen William LuZhili ZhengFrank J LoweryJared J GartnerTodd D PrickettPaul F RobbinsSteven A RosenbergPublished in: Journal for immunotherapy of cancer (2022)
This single-cell approach provides an efficient process to isolate antigen-specific TCRs for research and clinical applications.