Meta-Analytic Comparison of Global RNA Transcriptomes of Acute and Chronic Myeloid Leukemia Cells Reveals Novel Gene Candidates Governing Myeloid Malignancies.
Staša JurgecGregor JezernikMario GorenjakTomaž BüdefeldUroš PotočnikPublished in: Cancers (2022)
Our study revealed novel biomarkers and specific biological processes associated with AML and CML. Further studies are required to evaluate their value as molecular targets for managing and treating the myeloid malignancies.
Keyphrases
- chronic myeloid leukemia
- acute myeloid leukemia
- induced apoptosis
- dendritic cells
- bone marrow
- single cell
- liver failure
- cell cycle arrest
- respiratory failure
- copy number
- genome wide
- drug induced
- allogeneic hematopoietic stem cell transplantation
- intensive care unit
- immune response
- gene expression
- signaling pathway
- aortic dissection
- single molecule
- dna methylation
- acute respiratory distress syndrome
- transcription factor
- clinical evaluation