COVID-19 Vaccine Antibody Response in a Single-Center Urban Hemodialysis Unit.
Mingyue HeRui SongZakir ShaikCrystal A GadegbekuLouise EnderleChristina PetyoSally B QuinnZoe PfefferKathleen MurphySteven KelsenAaron D MishkinJean LeeAvrum GillespiePublished in: Vaccines (2023)
The patients naïve to COVID-19 exhibited an attenuated and foreshortened antibody response following two doses of the mRNA vaccines compared with the recovered patients, who maintained 100% APR before the booster dose. The 6-month booster dose counteracted declining immunity and stimulated antibody responses in the naïve patients, even in previously non-responsive patients. This observation implies that different booster vaccination strategies might be required for COVID-19-naïve and -recovered patients. Post-vaccination antibody testing may serve as a valuable tool for guiding vaccination strategies.