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Getting Fit to Counteract Cognitive Aging: Evidence and Future Directions.

Michelle W VossShivangi Jain
Published in: Physiology (Bethesda, Md.) (2022)
Physical activity has shown tremendous promise for counteracting cognitive aging, but also tremendous variability in cognitive benefits. We describe evidence for how exercise affects cognitive and brain aging, and whether cardiorespiratory fitness is a key factor. We highlight a brain network framework as a valuable paradigm for the mechanistic insight needed to tailor physical activity for cognitive benefits.
Keyphrases
  • physical activity
  • body mass index
  • resting state
  • machine learning
  • functional connectivity
  • artificial intelligence
  • blood brain barrier