Brachytherapy remains an underrecognized and underutilized radiation therapy modality for the treatment of spinal tumors. This article summarizes the existing body of medical literature on the usage, indications, techniques, and outcomes of brachytherapy for the treatment of spine tumors. The disease pathology most commonly treated with brachytherapy is metastatic spine cancer, rather than primary bone tumors of the spine. Brachytherapy can be used alone, as percutaneous needle injections; however, it is more often used in conjunction with open surgery or cement vertebral body augmentation. Although the data are still relatively sparse, studies show consistent benefit from brachytherapy in terms of improvements in pain, function, local recurrence rate, and overall survival. Brachytherapy is also associated with a favorable complication profile.
Keyphrases
- radiation therapy
- high dose
- locally advanced
- minimally invasive
- low dose
- ultrasound guided
- radiation induced
- spinal cord
- systematic review
- healthcare
- small cell lung cancer
- chronic pain
- bone mineral density
- machine learning
- type diabetes
- metabolic syndrome
- skeletal muscle
- acute coronary syndrome
- coronary artery disease
- soft tissue
- weight loss
- deep learning
- percutaneous coronary intervention
- postmenopausal women