Siponimod Inhibits the Formation of Meningeal Ectopic Lymphoid Tissue in Experimental Autoimmune Encephalomyelitis.

Rosa Margareta BrandJolien DiddensVerena FriedrichMonika PfallerHelena RadbruchBernhard Hemmer Katja Steiger Klaus Lehmann-Horn

Published in: Neurology(R) neuroimmunology & neuroinflammation (2021)

Beneficial effects on the disease course correlated with a reduction in mELT, suggesting that inhibition of mELT may be an additional mechanism of action of siponimod in the treatment of EAE. Further studies are needed to establish causality and confirm this observation in MS.

Keyphrases

mass spectrometry
multiple sclerosis
ms ms
emergency department
adverse drug