Prioritized polycystic kidney disease drug targets and repurposing candidates from pre-cystic and cystic mouse Pkd2 model gene expression reversion.
Elizabeth J WilkTimothy C HowtonJennifer L FisherVishal H OzaRyan T BrownleeKasi C McPhersonHannah L ClearyBradley K YoderJames F GeorgeMichal MrugBrittany N LasseignePublished in: Molecular medicine (Cambridge, Mass.) (2023)
Collectively, these results indicate drug targets and repurposing candidates that may effectively treat pre-cystic as well as cystic ADPKD.