Comparison of Plasma Exosome Proteomes Between Obese and Non-Obese Patients with Type 2 Diabetes Mellitus.
Yanjun WangYou WuShuangzhu YangYan ChenPublished in: Diabetes, metabolic syndrome and obesity : targets and therapy (2023)
The plasma exosome DEPs are potentially responsible for the development of obesity-related T2DM possibly through the insulin signaling pathway and the interaction with other proteins. Our study may guide future research direction toward the pathogenesis of obesity-related T2DM.
Keyphrases
- obese patients
- weight loss
- bariatric surgery
- type diabetes
- metabolic syndrome
- insulin resistance
- glycemic control
- roux en y gastric bypass
- signaling pathway
- gastric bypass
- adipose tissue
- high fat diet induced
- weight gain
- epithelial mesenchymal transition
- pi k akt
- induced apoptosis
- endoplasmic reticulum stress
- body mass index
- physical activity