Unraveling the Diversity of Co-Colonization by CPE.
Gabrielle LeviMor N Lurie-WeinbergerAlona Keren-PazAntoine O AndremontDavid SchwartzYehuda CarmeliPublished in: Microorganisms (2022)
Antibiotic-resistant bacteria, and more specifically, carbapenem-producing Enterobacterales (CPE) strains, are increasing worldwide. Despite their growing prevalence, in most high-income countries, the detection of CPE is still considered a low-frequency event. Sporadically, patients co-colonized with distinct CPE strains and/or different carbapenemase enzymes are detected. In this paper, we present three cases that illustrate the underlying mechanisms of co-colonization, focusing on horizontal gene transfer (HGT) and patient-to-patient transmission. We also demonstrate the diversity of CPE species and discuss the potential consequences of co-colonization.
Keyphrases
- escherichia coli
- klebsiella pneumoniae
- end stage renal disease
- acinetobacter baumannii
- case report
- ejection fraction
- newly diagnosed
- prognostic factors
- physical activity
- mental health
- peritoneal dialysis
- drug resistant
- gene expression
- copy number
- risk assessment
- cystic fibrosis
- pseudomonas aeruginosa
- climate change
- real time pcr
- loop mediated isothermal amplification
- quantum dots