In Silico and In vitro Assessment of Antibacterial Activity, LPS Binding Affinity, and Toxicity of the GKY25 Peptide.

Parisa AmiriMojdeh Hakemi-ValaAhmad NazarianFarnoosh BarnehKamran Pooshang Bagheri

Published in: Current pharmaceutical design (2023)

Gathering all in silico and in vitro data together, GKY25 is a good drug lead that could be examined further using clinical isolates of gram-negative bacteria in vitro.

Keyphrases

molecular docking
inflammatory response
electronic health record
oxidative stress
adverse drug
dna binding
binding protein
emergency department
molecular dynamics simulations
mass spectrometry