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Genetic variations on 31 and 450 residues of influenza A nucleoprotein affect viral replication and translation.

Su-Jhen HungYin-Mei HsuSheng-Wen HuangHuey-Pin TsaiLeo Yi Yang LeeAeron C HurtIan G BarrShin-Ru ShihJen-Ren Wang
Published in: Journal of biomedical science (2020)
These findings indicated variations identified in evolution have roles in modulating viral replication in vitro and in vivo. This study demonstrates that the interaction between variations of NP during virus evolution deserves future attention.
Keyphrases
  • sars cov
  • working memory
  • signaling pathway
  • gene expression
  • copy number