The potential failure risk of the cone-beam computed tomography-based planning target volume margin definition for prostate image-guided radiotherapy based on a prospective single-institutional hybrid analysis.
Katsumi HiroseMariko SatoYoshiomi HatayamaHideo KawaguchiFumio KomaiMakoto SohmaHideki ObaraMasashi SuzukiMitsuki TanakaIchitaro FujiokaKoji IchiseYoshihiro TakaiMasahiko AokiPublished in: Radiation oncology (London, England) (2018)
PTV margins calculated from CBCT-ST might be underestimated compared to the true PTV margins. To determine a reliable CBCT-ST-based PTV margin, at least the systemic error Σ and the random error σ for on-line matching errors need to be investigated by supportive preliminary FM evaluation at least once.