Association of CREBRF variants with obesity and diabetes in Pacific Islanders from Guam and Saipan.

Robert L HansonSaied SafabakhshJeffrey M CurtisWen-Chi HsuehLois I JonesTanisha F AflagueJenny Duenas SarmientoSatish KumarNicholas B BlackburnJoanne E CurranDarin MahkeeLeslie J BaierWilliam C KnowlerRobert G Nelson

Published in: Diabetologia (2019)

These results confirm the associations of CREBRF variants with higher BMI and lower risk of diabetes and, importantly, they suggest that these variants contribute to the risk of obesity and diabetes in Oceanic populations.

Keyphrases

type diabetes
glycemic control
copy number
cardiovascular disease
insulin resistance
metabolic syndrome
weight loss
weight gain
high fat diet induced
body mass index
gene expression
skeletal muscle
genome wide